The Institute of Chemical Biology and Fundamental Medicine of the Siberian Branch of the Russian Academy of Sciences is one of the international leaders in creation of gene-directed biologically active agents, studying of physico-chemical bases of processes of transfering and saving of hereditary information. Genodiagnostic of infectious, autoimmune and tumoral diseases are also studied at the Institute. The Institute provides production of enzymes for biotechnology and medical diagnostics (DNA ligases, DNA polymerases, nucleases), synthesis of oligonucleotides, nucleosidtriphosphates. According to the SCImago Institutions Rankings (2013) based on percentage of publications in top international journals, ICBFM RAS is on the second place among the Russian biological institutes and fifteenth place among all Russian scientific organizations.
The structure of the Institute includes:
- 16 Laboratories and research groups;
- “Genomics” Core Facility of the Siberian Branch of the Russian Academy of Sciences;
- Center of New Medical Technologies of the Siberian Branch of the Russian Academy of Sciences;
- Interdisciplinary “Russian-American Laboratory of Biomedical Chemistry” (head of the Laboratory Sidney Altman - Nobel winner, USA).
- Joint Center for genomic, proteomic and metabolomics studies
Since 2000 on the basis of ICBFM the “Genomics” Core Facility exists, which ensures needs of Siberian academic community in DNA sequencing (from standard definition of nucleic acids sequences to high performance sequencing - Next Generation Sequencing). In 2006 on the basis of Institute was created the Center of New Medical Technologies SB RAS, in which approbation of new development and technologies of institutes of SB RAS take place. 163 Researchers work at the Institute, among them: 2 academicians of the Russian Academy of Sciences, 1 correspondent member of the Russian Academy of Sciences, 24 doctors of science, 102 candidates of science (PhD). The winners of the State prizes, awards of the Government of the Russian Federation, and number of other prestigious Russian and international awards work at the ICBFM SB RAS.